Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 5/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | PCNA | P12004 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355060 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BSLC7A5PTPN1PPARA | |
| SCHEMBL879605 | 0.78 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL3504346 | 0.78 | SLC7A5 (0.43) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL18477652 | 0.77 | SLC7A5 (0.46) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL27293069 | 0.76 | SLC7A5 (0.53) | SLC7A5PTPN1PTGS1ALPIPKM | |
| SCHEMBL659105 | 0.76 | SLC7A5 (0.69) | ITGB3ITGA2BSLC7A5PTGS1ALPI | |
| SCHEMBL288912 | 0.76 | SLC7A5 (0.69) | ITGB3ITGA2BSLC7A5PTGS1ALPI | |
| SCHEMBL515522 | 0.76 | SLC7A5 (0.69) | ITGB3ITGA2BSLC7A5PTGS1ALPI | |
| SCHEMBL1874526 | 0.75 | ITGB3 (0.64) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 | |
| SCHEMBL1874524 | 0.75 | ITGB3 (0.64) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015924-A2 | HYBRID OLIGONUCLEOTIDES | ENTRADA THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2023192510-A1 | β-CATENIN ANTIBODIES | ENTRADA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023034818-A1 | COMPOSITIONS AND METHODS FOR SKIPPING EXON 45 IN DUCHENNE MUSCULAR DYSTROPHY | ENTRADA THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |