Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25248388 | 0.87 | TAAR1 (0.47) | TAAR1MPOSLC6A4CYP2A6 | |
| Hydrochloric Acid SCHEMBL25390767 | 0.86 | TAAR1 (0.46) | MAOBTAAR1MPOSLC6A4IDO1 | |
| SCHEMBL31426239 | 0.83 | MAOB (0.37) | MAOBIDO1 | |
| SCHEMBL25004730 | 0.81 | GABRA1 (0.42) | — | |
| SCHEMBL27390138 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL31426265 | 0.72 | BACE1 (0.36) | IDO1 | |
| SCHEMBL16126075 | 0.71 | CYP2A6 (0.42) | MAOBCYP2A6 | |
| SCHEMBL31426304 | 0.71 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL25019378 | 0.71 | GSK3B (0.30) | — | |
| SCHEMBL15345559 | 0.70 | TAAR1 (0.46) | MAOBPNMTTAAR1MPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4148056-A1 | SOS1 INHIBITOR CONTAINING PHOSPHORUS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-03-15 | — | — | EP | disclosed |