SCHEMBL25117604

SCHEMBL25117604

C1=CC(c2ccccc2)Cc2[nH]c3ccccc3c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.41
DRD1 P21728 1/20 0.41
DRD5 P21918 1/20 0.41
NR2E1 Q9Y466 2/20 0.38
CYP2D6 P10635 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
HTR7 P34969 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GPR3 P46089 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21671134 0.83 TNKS2 (0.40) DRD2DRD1DRD5MAPTMEN1
SCHEMBL15926424 0.78 KDM4E (0.43) DRD2DRD1DRD5NR2E1CYP2D6
SCHEMBL24343231 0.78 NR2E1 (0.40) NR2E1CYP2D6SIGMAR1CYP2C19MAPT
SCHEMBL25617839 0.75 PIM1 (0.40) MAPK1MAPTALDH1A1HSD17B10MEN1
SCHEMBL17880964 0.73
SCHEMBL24727404 0.70
SCHEMBL5876273 0.68 CSF1R (0.36) HTR7CYP3A4MAPK1LMNAKMT2A
SCHEMBL5876644 0.68 MAPK10 (0.46) HTR7LMNAMAPTSMN1; SMN2ALDH1A1
SCHEMBL20309452 0.67 ALDH1A1 (0.36) DRD2DRD1DRD5CYP2D6HTR7
SCHEMBL19752575 0.66 GPR3 (0.35) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230107166-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LG DISPLAY CO., LTD. (KR) 2023-04-06 US disclosed