Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293413 | 0.80 | PNMT (0.31) | GPR3PNMT | |
| SCHEMBL23281513 | 0.78 | GPR3 (0.38) | GPR3PNMT | |
| SCHEMBL18506308 | 0.78 | GPR3 (0.38) | GPR3PNMT | |
| SCHEMBL23302722 | 0.67 | GPR3 (0.44) | GPR3PNMTLIMK1 | |
| SCHEMBL25117604 | 0.66 | DRD2 (0.41) | GPR3 | |
| SCHEMBL21942163 | 0.66 | — | — | |
| SCHEMBL13450600 | 0.65 | GPR3 (0.41) | GPR3PNMTLIMK1CDK5CDK5R1 | |
| SCHEMBL8713123 | 0.63 | NFKB1 (0.48) | — | |
| SCHEMBL21941917 | 0.62 | GPR3 (0.35) | GPR3PNMT | |
| SCHEMBL23430379 | 0.62 | GPR3 (0.39) | GPR3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260438-A1 | DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME | LG Chem, Ltd. (KR) | 2017-12-27 | — | — | EP | disclosed |