Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319009 | 0.92 | FAAH (0.37) | MAPK1FAAHMGLL | |
| SCHEMBL26134119 | 0.89 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL20625499 | 0.86 | LPL (0.31) | — | |
| SCHEMBL26132129 | 0.83 | SIGMAR1 (0.33) | — | |
| SCHEMBL31334888 | 0.82 | SIGMAR1 (0.37) | — | |
| SCHEMBL16372532 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL31705089 | 0.78 | SIGMAR1 (0.35) | FAAHMGLL | |
| SCHEMBL1534508 | 0.75 | CD274 (0.35) | — | |
| SCHEMBL18010602 | 0.73 | FFAR1 (0.43) | MAPK1 | |
| SCHEMBL17102316 | 0.73 | FFAR1 (0.43) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379523-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | Incyte Corporation (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010075270-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | INCYTE CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |