Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30318930 | 1.00 | GPR119 (0.48) | GPR119DRD2DRD3MEN1KMT2A | |
| SCHEMBL2191501 | 0.88 | SETD7 (0.47) | GPR119HCRTR1HCRTR2ALDH1A1LMNA | |
| SCHEMBL2195828 | 0.88 | SETD7 (0.47) | DRD2DRD3HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL25120379 | 0.87 | NPC1 (0.54) | DRD2DRD3MEN1KMT2AHCRTR1 | |
| SCHEMBL25120365 | 0.87 | MGLL (0.49) | DRD2DRD3MEN1KMT2AHCRTR1 | |
| SCHEMBL2194541 | 0.85 | F10 (0.48) | DRD2DRD3MEN1KMT2AHCRTR1 | |
| SCHEMBL30318932 | 0.85 | F10 (0.48) | DRD2DRD3MEN1KMT2AHCRTR1 | |
| SCHEMBL25120224 | 0.84 | KDM4E (0.50) | GPR119EPHX2 | |
| SCHEMBL2194586 | 0.84 | FAAH (0.48) | GPR119EPHX2ALDH1A1LMNA | |
| SCHEMBL2196624 | 0.84 | MEN1 (0.47) | GPR119MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049808-A2 | SMALL MOLECULE INHIBITORS OF TEAD-YAP | THE GENERAL HOSPITAL CORPORATION (US) | 2023-03-30 | — | — | WO | disclosed |