Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290150 | 0.88 | CACNA1G (0.55) | DRD2MAPTTP53CACNA1GDRD3 | |
| SCHEMBL2486143 | 0.79 | HRH3 (0.70) | — | |
| SCHEMBL7283381 | 0.78 | CACNA1G (0.60) | DRD2MAPTSLC6A4CACNA1GDRD3 | |
| SCHEMBL6843584 | 0.75 | DRD2 (0.54) | DRD4DRD2MAPTSLC6A2SLC6A4 | |
| SCHEMBL7283745 | 0.74 | DRD3 (0.50) | DRD4DRD2SLC6A2SLC6A4DRD3 | |
| SCHEMBL2512341 | 0.73 | ACP1 (0.55) | DRD2SLC6A2SLC6A4 | |
| SCHEMBL2488597 | 0.71 | HRH3 (0.76) | — | |
| SCHEMBL6846732 | 0.71 | MAPT (0.54) | DRD4KDM4EDRD2MAPTTP53 | |
| SCHEMBL11447942 | 0.70 | HTR7 (0.60) | DRD4DRD2MAPTSLC6A4TP53 | |
| SCHEMBL10995656 | 0.70 | MAPT (0.58) | KDM4EGAADRD2MAPTDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609031-B1 | Process for preparing benzothiazepine derivatives | SHIONOGI & CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0609031-A1 | Process for preparing benzothiazepine derivatives | SHIONOGI & CO., LTD. (JP) | 1994-08-03 | — | — | EP | disclosed |