Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839074 | 0.98 | FKBP1A (0.66) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL31634201 | 0.85 | HPGD (0.72) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL1853129 | 0.81 | POLB (0.71) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL28210752 | 0.81 | KEAP1 (0.52) | FKBP1AKMT2AGLAALDH1A1HTT | |
| SCHEMBL4001428 | 0.81 | POLB (0.56) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL30916886 | 0.81 | FKBP1A (0.47) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL4710815 | 0.81 | HTR6 (0.51) | FKBP1AKMT2AGLA | |
| SCHEMBL18424892 | 0.80 | FKBP1A (0.46) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL31634176 | 0.78 | FKBP1A (0.55) | FKBP1AKMT2AGLAALDH1A1LMNA | |
| SCHEMBL10192123 | 0.78 | FKBP1A (0.64) | FKBP1AKMT2AGLAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121031-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | Atux Iskay LLC (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021188949-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2019079706-A1 | AMINOGLYCOSIDE ANTIBIOTICS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-04-25 | — | — | WO | disclosed |
| CN-105001278-B | A kind of synthetic method of Fondaparinux sodium disaccharides intermediate fragments | 天津红日药业股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| EP-3004060-A1 | COMPOUNDS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2016-04-13 | — | — | EP | disclosed |
| CN-105001278-A | Synthesis method for fondaparinux sodium disaccharide intermediate segment | TIANJIN CHASESUN PHARM CO LTD | 2015-10-28 | — | — | CN | disclosed |
| WO-2014194127-A1 | COMPOUNDS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2014-12-04 | — | — | WO | disclosed |
| EP-2376454-A2 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | Schering Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010059611-A2 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-05-27 | — | — | WO | disclosed |
| EP-2041085-A1 | PYRROLE DERIVATIVES AND THEIR METHODS OF USE | Abbott Laboratories (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008002974-A1 | PYRROLE DERIVATIVES AND THEIR METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-01-03 | — | — | WO | disclosed |
| US-6964974-B2 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2005-11-15 | — | — | US | disclosed |