SCHEMBL2512467

SCHEMBL2512467

CCCCC1=Cc2c(-c3ccc(CC)cc3)cccc2C1[Zr](Cl)(Cl)(C1C(CCCC)=Cc2c(-c3ccc(CC)cc3)cccc21)[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2515731 0.96 GPR3 (0.32)
SCHEMBL2508943 0.94 RARB (0.34)
SCHEMBL2511496 0.93 RARB (0.31)
SCHEMBL2511688 0.93 EDNRB (0.31) EDNRBEDNRA
SCHEMBL2518453 0.91 RARB (0.36)
SCHEMBL2511689 0.91 RARB (0.36)
SCHEMBL2514626 0.91 RARB (0.33)
SCHEMBL5351724 0.91 RARB (0.33)
SCHEMBL2518430 0.90 RARB (0.36)
SCHEMBL2518343 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US claimed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US claimed
US-8034886-B2 Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts TICONA GMBH (DE) 2011-10-11 US disclosed
US-20100056737-A1 Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2010-03-04 US disclosed
US-7598329-B2 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts TICONA GMBH (DE) 2009-10-06 US disclosed
US-20070105712-A1 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2007-05-10 US disclosed
US-7202190-B1 Supported catalyst system for the polymerization of olefins TARGOR GMBH (DE) 2007-04-10 US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 US disclosed
US-7034173-B2 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-04-25 US disclosed
US-6953829-B2 Catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2005-10-11 US disclosed
US-6576723-B1 Coordination catalyst comprising metallocene, organoboroaluminum, Lewis base and organometallic compound BASELL POLYOLEFINE GMBH (DE) 2003-06-10 US disclosed
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins SCHOTTEK JORG (DE) 2003-04-10 US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 US disclosed
US-20030008984-A1 Novel catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2003-01-09 US disclosed
US-6500908-B1 ORGANOBORON-ALUMINUM COMPOUND, METALLOCENE, COCATALYTICALLY ACTIVE COMPOUND; BIS(DIMETHYLALUMINOXY)PENTAFLUOROPHENYLBORANE; OLEFIN POLYMERIZATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2002-12-31 US disclosed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 US disclosed
US-6417302-B1 REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2002-07-09 US disclosed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins CLIC1, HACL2, ADH1C EDNRB 4707/4885EDNRA 4787/4885AGTR1 209/4885
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins SCO2, CNOT1, CYC1 EDNRB 4456/4885EDNRA 4658/4885AGTR1 3955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.