SCHEMBL25126239

SCHEMBL25126239

C=C/C=C\N(CCCC(=C)CCCCCCCCCCCCCC)C(=C)C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.34
FASN P49327 1/20 0.32
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29116361 0.71 FASN (0.54) FAAHFASNTSHRMEN1ALDH1A1
SCHEMBL17517801 0.71 MMP1 (0.31)
SCHEMBL20774476 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854580 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854579 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854578 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854575 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854584 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL20854574 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A
SCHEMBL21660228 0.70 CES2 (0.52) TSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023056033-A1 LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES ORNA THERAPEUTICS, INC. (US) 2023-04-06 WO disclosed