Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129816 | 0.88 | ALDH1A1 (0.39) | SIRT6SIRT1TLR2ALDH1A1NMT2 | |
| SCHEMBL23191786 | 0.86 | SIRT6 (0.36) | SIRT6SIRT1BCHETLR2ALDH1A1 | |
| SCHEMBL29318735 | 0.85 | EPHX1 (0.35) | SIRT6SIRT1ALDH1A1KDM4ENMT2 | |
| SCHEMBL23191820 | 0.84 | SIRT6 (0.33) | SIRT6SIRT1BCHETLR2ALDH1A1 | |
| SCHEMBL25132958 | 0.84 | CPB2 (0.39) | SIRT6SIRT1BCHETLR2ALDH1A1 | |
| SCHEMBL26003071 | 0.83 | SIRT6 (0.35) | SIRT6SIRT1BCHETLR2ALDH1A1 | |
| SCHEMBL14378775 | 0.83 | SIRT6 (0.35) | SIRT6SIRT1BCHETLR2DPP7 | |
| SCHEMBL25129814 | 0.82 | ALDH1A1 (0.49) | BCHEALDH1A1USP2TSHR | |
| SCHEMBL14378774 | 0.82 | SIRT6 (0.34) | SIRT6SIRT1BCHETLR2DPP7 | |
| SCHEMBL25129824 | 0.81 | NMT1 (0.46) | SIRT6SIRT1TLR2NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |