Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 4/20 | 0.34 |
| ▸ | CCR8 | P51685 | 4/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130855 | 0.79 | CSNK2A1 (0.34) | CCR1CCR8CCR5MEN1KMT2A | |
| SCHEMBL2171048 | 0.74 | CCR1 (0.39) | CCR1CCR8CCR5MEN1KMT2A | |
| SCHEMBL2172222 | 0.71 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL31729412 | 0.71 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL25130637 | 0.71 | AXL (0.49) | — | |
| SCHEMBL20448901 | 0.69 | NR4A2 (0.34) | CCR1CCR8MEN1KMT2AKDM4E | |
| SCHEMBL11769852 | 0.69 | NR4A2 (0.38) | CCR1CCR8CCR5MEN1KMT2A | |
| SCHEMBL20292984 | 0.67 | NSD2 (0.40) | MEN1KMT2AALDH1A1MAPTAPAF1 | |
| SCHEMBL28712027 | 0.67 | PDE5A (0.46) | KDM4EUSP2ALDH1A1MAPT | |
| SCHEMBL29472084 | 0.67 | PDE5A (0.46) | KDM4EUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051628-A1 | SOS1 INHIBITORS HAVING PYRIDO SIX-MEMBERED RING STRUCTURE | 上海海和药物研究开发股份有限公司 | 2023-04-06 | — | — | WO | disclosed |