Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511102 | 0.82 | HPGD (0.36) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2511103 | 0.82 | HPGD (0.36) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL192940 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL616961 | 0.72 | CRHBP (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1956908 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30480716 | 0.72 | CRHBP (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29935616 | 0.72 | CYP1A2 (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30855444 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1957022 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19961719 | 0.71 | MAPK1 (0.56) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379544-B1 | ISOXAZOLINES DERIVATIVES AND THEIR USE AS PESTICIDE | NOVARTIS AG (CH) | 2013-10-16 | — | — | EP | disclosed |
| US-8377942-B2 | Isoxazolines derivatives and their use as pesticide | NOVARTIS AG (CH) | 2013-02-19 | — | — | US | disclosed |
| US-20110245274-A1 | ISOXAZOLINES DERIVATIVES AND THEIR USE AS PESTICIDE | NOVARTIS AG (CH) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245274-A1 | ISOXAZOLINES DERIVATIVES AND THEIR USE AS PESTICIDE | ACHE, PRDX5, VDAC3 | ALDH1A1 1797/4885KDM4E 2481/4885SMN1; SMN2 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.