SCHEMBL25137367

SCHEMBL25137367

COC(=C(C#N)C#N)N(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42
FAAH O00519 1/20 0.39
PHGDH O43175 1/20 0.39
MGLL Q99685 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 2/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.36
RAB9A P51151 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137365 0.77 FAAH (0.44) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL27130360 0.77 L3MBTL1 (0.47) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL15494493 0.76 FAAH (0.42) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL25137326 0.74 L3MBTL1 (0.44) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL25137334 0.74 FAAH (0.41) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL25137263 0.73 L3MBTL1 (0.43) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL15494364 0.72 FAAH (0.47) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL25137333 0.71 FAAH (0.43) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL23033319 0.69 FAAH (0.44) L3MBTL1LMNAFAAHPHGDHMGLL
SCHEMBL4690778 0.69 L3MBTL1 (0.47) L3MBTL1LMNAFAAHPHGDHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP L3MBTL1 1668/4885LMNA 2541/4885FAAH 2818/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP L3MBTL1 1668/4885LMNA 2541/4885FAAH 2818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.