SCHEMBL25137263

SCHEMBL25137263

CO/C(=C(\C)c1ccccc1)N(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
FAAH O00519 1/20 0.40
PHGDH O43175 1/20 0.40
MGLL Q99685 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
TSHR P16473 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137326 0.83 L3MBTL1 (0.44) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137258 0.82 ALDH1A1 (0.43) L3MBTL1LMNANPC1RAB9ATSHR
SCHEMBL27130360 0.82 L3MBTL1 (0.47) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137267 0.76 FAAH (0.45) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137262 0.73 FAAH (0.42) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137367 0.73 L3MBTL1 (0.42) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137266 0.70 FAAH (0.44) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137264 0.69 TSHR (0.50) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL18772417 0.69 TSHR (0.50) L3MBTL1LMNAHTTNPC1RAB9A
SCHEMBL25137356 0.68 ALDH1A1 (0.45) NPC1RAB9ATSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP L3MBTL1 1668/4885LMNA 2541/4885HTT 2222/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP L3MBTL1 1668/4885LMNA 2541/4885HTT 2222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.