SCHEMBL25137488

SCHEMBL25137488

CN(Cc1cccc(C(=C(N(C)c2ccccc2)N(C)c2ccccc2)c2ccccc2)c1)C(=C(c1ccccc1)c1ccccc1)N(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MEN1 O00255 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.45
AOC3 Q16853 2/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
MDM2 Q00987 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
GAA P10253 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25137259 0.79 FAAH (0.47) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL30036639 0.72 L3MBTL1 (0.55) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL25137261 0.72 FAAH (0.44) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL4836068 0.69 MEN1 (0.63) KMT2AMEN1AOC3NPC1RAB9A
SCHEMBL18780834 0.69 L3MBTL1 (0.57) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL13525179 0.69 L3MBTL1 (0.57) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL11275517 0.68 NPC1 (0.59) KMT2AMEN1NPC1RAB9ACA12
SCHEMBL1696343 0.67 L3MBTL1 (0.55) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL30036881 0.67 L3MBTL1 (0.55) KMT2AMEN1L3MBTL1NPC1RAB9A
SCHEMBL9044900 0.66 NPC1 (0.52) KMT2AMEN1AOC3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KMT2A 4312/4885MEN1 4145/4885L3MBTL1 1668/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP KMT2A 4312/4885MEN1 4145/4885L3MBTL1 1668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.