SCHEMBL2513837

SCHEMBL2513837

O=P(O)(OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)[C@H](O)[C@@H]1O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 10/20 0.67
P2RX3 P56373 5/20 0.67
P2RX1 P51575 3/20 0.67
P2RY2 P41231 2/20 0.67
P2RX4 Q99571 2/20 0.67
P2RX2 Q9UBL9 2/20 0.67
ALDH1A1 P00352 2/20 0.67
SRC P12931 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
P2RY11 Q96G91 2/20 0.63
ENPP1 P22413 2/20 0.63
P2RY6 Q15077 1/20 0.63
MACROD2 A1Z1Q3 1/20 0.63
SIRT6 Q8N6T7 1/20 0.63
MACROD1 Q9BQ69 1/20 0.63
TRPM2 O94759 1/20 0.63
P2RY12 Q9H244 1/20 0.61
RNASEL Q05823 1/20 0.59
TGM2 P21980 1/20 0.59
CA5A P35218 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL625182 0.97 P2RY1 (0.68) P2RY1P2RX3P2RX1P2RY2P2RX4
SCHEMBL10454900 0.96 P2RY1 (0.67) P2RY1P2RX3P2RX1P2RY2P2RX4
Triphosphate SCHEMBL11811171 0.92 CA5A (0.64) P2RY1P2RX3P2RX1P2RY2P2RX4
SCHEMBL188740 0.92 CA5A (0.68) P2RY1P2RY2SRCSMN1; SMN2P2RY11
Ammonia Solution, Strong SCHEMBL4362929 0.91 CA5A (0.67) P2RY1P2RY2SRCSMN1; SMN2P2RY11
Guanosine Triphosphate SCHEMBL15900104 0.88 P2RY1 (0.70) P2RY1P2RX3P2RX1P2RY2P2RX4
Gtp SCHEMBL15900105 0.88 P2RY1 (0.70) P2RY1P2RX3P2RX1P2RY2P2RX4
SCHEMBL1942566 0.88 RNASEL (0.68) P2RY1P2RY2SRCSMN1; SMN2P2RY11
SCHEMBL15794408 0.87 P2RY1 (0.79) P2RY1P2RX3P2RX1P2RY2P2RX4
SCHEMBL1904678 0.87 P2RY1 (0.66) P2RY1P2RX3P2RX1P2RY2P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed