SCHEMBL188740

SCHEMBL188740

O=P(O)(O)OC[C@H]1O[C@@H](n2cnc3c(O)nc(O)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.68
DNPH1 O43598 6/20 0.66
TAS1R3 Q7RTX0 4/20 0.66
TAS1R1 Q7RTX1 4/20 0.66
PRKAB2 O43741 1/20 0.66
TRPM2 O94759 1/20 0.66
LDHA P00338 1/20 0.66
ADRB2 P07550 1/20 0.66
FBP1 P09467 1/20 0.66
SRC P12931 1/20 0.66
ADORA1 P30542 1/20 0.66
P2RY2 P41231 1/20 0.66
P2RY1 P47900 1/20 0.66
PRKAG1 P54619 1/20 0.66
PRKAA2 P54646 1/20 0.66
PDE4D Q08499 1/20 0.66
KCNH2 Q12809 1/20 0.66
PRKAA1 Q13131 1/20 0.66
PDE3A Q14432 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4362929 0.99 CA5A (0.67) CA5ADNPH1TAS1R3TAS1R1PRKAB2
Triphosphate SCHEMBL11811171 0.96 CA5A (0.64) CA5ADNPH1TAS1R3TAS1R1PRKAB2
SCHEMBL10454900 0.92 P2RY1 (0.67) SRCP2RY2P2RY1SMN1; SMN2P2RY11
SCHEMBL2513837 0.92 P2RY1 (0.67) CA5ATRPM2SRCP2RY2P2RY1
SCHEMBL27183159 0.92 CA5A (0.66) CA5ADNPH1TAS1R3TAS1R1PRKAB2
SCHEMBL1942566 0.92 RNASEL (0.68) CA5ADNPH1TAS1R3TAS1R1PRKAB2
SCHEMBL625182 0.91 P2RY1 (0.68) SRCP2RY2P2RY1SMN1; SMN2P2RY11
SCHEMBL13177076 0.91 CA5A (0.57) CA5ADNPH1TAS1R3TAS1R1PRKAB2
SCHEMBL6848973 0.91 P2RY1 (0.67) CA5ADNPH1TAS1R3TAS1R1PRKAB2
E626 SCHEMBL19222125 0.91 CA5A (0.71) CA5ADNPH1TAS1R3TAS1R1PRKAB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2254 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
CN-122075713-A Deaminase and use of transaminase in the treatment of polyglutamine diseases 2026-05-26 CN claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
US-12605342-B2 Polymer-encapsulated drug particles TONIC MEDICAL, INC. (US) 2026-04-21 US claimed
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US claimed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP claimed
CN-120195409-A Composition for diagnosing sepsis and medicament for sepsis preventive treatment 北京大学第三医院(北京大学第三临床医学院) 2025-06-24 CN claimed
CN-119968093-A Hole transport material, hole transport layer and solar cell thereof 天合光能股份有限公司 2025-05-09 CN claimed
CN-119894495-A Method for reducing wrinkle and crease appearance using small molecule compounds 伯奇生物医药有限公司 2025-04-25 CN claimed
US-12280226-B2 Drug-coated balloon catheters for body lumens UROTRONIC, INC. (US) 2025-04-22 US claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
EP-0185092-B1 PROCESS FOR PREPARING 5'-GUANYLIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-10-07 EP claimed
EP-0251489-B1 PROCESS FOR PRODUCING 5'-GUANYLIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-07-22 EP claimed
US-5034378-A Flavor enhancers for food of sodium chloride, potassium chloride, monosodium glutamate and fibers Cox, James P. (US) 1991-07-23 US claimed
US-4960696-A Process for producing physiololgically active substance by multienzyme process Imahori, Kazutomo (JP) 1990-10-02 US claimed
EP-0263716-A2 A process for the preparation of 5'-guanylic acid and expression vectors for use therein KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1988-04-13 EP claimed
EP-0185092-A1 PROCESS FOR PREPARING 5'-GUANYLIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1986-06-25 EP claimed
US-4577012-A ABSORPTION ON ACTIVATED CARBON, ELUTION WITH ALKALI HYDROXIDE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-18 US claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 US claimed