SCHEMBL2513868

SCHEMBL2513868

OC(COCC1CC2CCC1C2)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
MCHR1 Q99705 1/20 0.31
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23011610 0.78 MEN1 (0.36) MEN1NPC1RAB9AKMT2A
SCHEMBL14479563 0.78 MEN1 (0.36) MEN1NPC1RAB9AKMT2A
SCHEMBL18409740 0.78 MEN1 (0.36) MEN1NPC1RAB9AKMT2A
SCHEMBL14632271 0.78 MEN1 (0.36) MEN1NPC1RAB9AKMT2A
SCHEMBL75232 0.78 MEN1 (0.36) MEN1NPC1RAB9AKMT2A
SCHEMBL6384052 0.76 MCHR1 (0.39) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL14252151 0.75 MEN1 (0.34) MEN1NPC1RAB9AKMT2A
SCHEMBL13764367 0.73 ATM (0.35)
SCHEMBL6853758 0.72 MEN1 (0.33) MEN1NPC1RAB9AKMT2A
SCHEMBL12332843 0.72 MEN1 (0.33) MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130323644-A1 NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESS USING SUCH COMPOSITIONS PROMERUS, LLC (US) 2013-12-05 US disclosed
US-8541523-B2 Norbornene-type polymers, compositions thereof and lithographic process using such compositions PROMERUS, LLC (US) 2013-09-24 US disclosed
US-20110244400-A1 Norbornene-Type Polymers, Compositions Thereof and Lithographic Process Using Such Compositions PROMERUS LLC (US) 2011-10-06 US disclosed