Ethyl Fumarate

Ethyl Fumarate

SCHEMBL251387

C=CC=CC=Cc1ccccc1.CCOC(=O)C=CC(=O)O

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.53
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
LMNA P02545 5/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HDAC3 O15379 1/20 0.42
TNKS O95271 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4193756 0.90 CA12 (0.47) CA12CA1CA2CA7CA9
Acrylic Acid Ethyl Ester SCHEMBL580632 0.88 LMNA (0.49) CA12CA1CA2CA7CA9
SCHEMBL8181765 0.86 MEN1 (0.46) HCAR2CA12CA1CA9LMNA
Maleic Acid SCHEMBL2777446 0.84 HDAC3 (0.59) HCAR2CA12CA1CA2CA7
Juarezic Acid SCHEMBL1859680 0.84 RAB9A (0.48) HCAR2CA12CA1CA2CA7
Ethyl Fumarate SCHEMBL8427380 0.83 HCAR2 (0.62) HCAR2CA12CA1CA2CA7
Ethyl Fumarate SCHEMBL8427384 0.83 HCAR2 (0.62) HCAR2CA12CA1CA2CA7
Ethyl Fumarate SCHEMBL1063586 0.83 HCAR2 (0.51) HCAR2CA12CA1CA2CA7
SCHEMBL3685506 0.83 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL5613524 0.83 CA12 (0.57) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088544-B2 Core-shell polymer nanoparticles and method of making emulsion aggregation particles using same XEROX CORPORATION (US) 2012-01-03 US claimed
US-20090035686-A1 CORE-SHELL POLYMER NANOPARTICLES AND METHOD OF MAKING EMULSION AGGREGATION PARTICLES USING SAME XEROX CORPORATION (US) 2009-02-05 US claimed
US-7291437-B2 Toner processes XEROX CORPORATION (US) 2007-11-06 US claimed
US-7208257-B2 Electron beam curable toners and processes thereof XEROX CORPORATION (US) 2007-04-24 US claimed
US-7001702-B2 Toner processes XEROX CORPORATION (US) 2006-02-21 US claimed
US-20050287464-A1 Electron beam curable toners and processes thereof XEROX CORPORATION 2005-12-29 US claimed
US-20050048389-A1 Toner processes XEROX CORPORATION 2005-03-03 US claimed
US-20040202950-A1 Toner processes XEROX CORPORATION. 2004-10-14 US claimed
US-20040202952-A1 Toner processes XEROX CORPORATION 2004-10-14 US claimed
US-6803166-B2 Toner processes XEROX CORPORATION 2004-10-12 US claimed
US-20040162373-A1 Toner processes XEROX CORPORATION 2004-08-19 US claimed
US-9045651-B2 Antifouling surfaces, methods of manufacture thereof and articles comprising the same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-06-02 US disclosed
US-8841055-B2 Super low melt emulsion aggregation toners comprising a trans-cinnamic di-ester XEROX CORPORATION (US) 2014-09-23 US disclosed
US-20130266896-A1 SUPER LOW MELT EMULSION AGGREGATION TONERS COMPRISING A TRANS-CINNAMIC DI-ESTER XEROX CORPORATION (US) 2013-10-10 US disclosed
EP-2028550-B1 Method for making emulsion aggregation particles using core-shell polymer nanoparticles XEROX CORP (US) 2012-08-15 EP disclosed
US-20050287464-A1 Electron beam curable toners and processes thereof XEROX CORPORATION 2005-12-29 US disclosed
EP-1610186-A2 Electron beam curable toners and processes thereof Xerox Corporation (US) 2005-12-28 EP disclosed
US-20050048389-A1 Toner processes XEROX CORPORATION 2005-03-03 US disclosed
US-6803166-B2 Toner processes XEROX CORPORATION 2004-10-12 US disclosed
US-20040162373-A1 Toner processes XEROX CORPORATION 2004-08-19 US disclosed