SCHEMBL8181765

SCHEMBL8181765

C=C(C=CC(=O)O)C(=O)OCC.C=CC=CC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 7/20 0.46
KDM4E B2RXH2 4/20 0.46
LMNA P02545 2/20 0.46
RAB9A P51151 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPC1 O15118 2/20 0.43
MAPT P10636 3/20 0.41
CTDSP1 Q9GZU7 1/20 0.40
HDAC3 O15379 2/20 0.40
HDAC4 P56524 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC7 Q8WUI4 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC10 Q969S8 2/20 0.40
HDAC11 Q96DB2 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756945 0.94 MEN1 (0.51) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL16619261 0.87 HCAR2 (0.39) MEN1KMT2AALDH1A1KDM4ELMNA
Ethyl Fumarate SCHEMBL251387 0.86 HCAR2 (0.53) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL11066534 0.86 MEN1 (0.51) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL8014931 0.86 MEN1 (0.54) MEN1KMT2AALDH1A1KDM4ELMNA
Maleic Acid SCHEMBL17504861 0.86 MEN1 (0.54) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL1860184 0.85 LMNA (0.50) MEN1KMT2AALDH1A1KDM4ELMNA
Styrene SCHEMBL7123463 0.84 MEN1 (0.53) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL2061765 0.84 ALDH1A1 (0.50) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL8166266 0.82 ALDH1A1 (0.54) MEN1KMT2AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093529-A COMPRISING A SUPPORT, A PHOTOTHERMOGRAPHIC IMAGE-FORMING LAYER COMPRISING ORGANIC SILVER SALT, LIGHT-SENSITIVE SILVER HALIDE REDUCING AGENT AND BINDER WITH A PROTECTIVE COATING CONTAINING A POLYVALENT METAL SALT OF PHTHALIC ACID; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2000-07-25 US disclosed