SCHEMBL25138714

SCHEMBL25138714

CCn1c(SCC(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)nnc1-c1ccco1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.63
▸ ALDH1A1 P00352 11/20 0.63
▸ HPGD P15428 3/20 0.63
▸ TP53 P04637 1/20 0.63
▸ KMT2A Q03164 2/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ HSD17B10 Q99714 6/20 0.57
▸ NPC1 O15118 3/20 0.57
▸ RAB9A P51151 3/20 0.57
▸ LMNA P02545 2/20 0.57
▸ ALOX15 P16050 2/20 0.57
▸ TSHR P16473 2/20 0.57
▸ MAPK1 P28482 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ CPB1 P15086 1/20 0.54
▸ RECQL P46063 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4198470 0.87 MAPT (0.69) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL29331809 0.84 MAPT (0.65) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL4211061 0.83 ALDH1A1 (0.75) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL4208560 0.83 ALDH1A1 (0.75) ALDH1A1HPGDTP53KMT2AMEN1
SCHEMBL4208837 0.83 ALDH1A1 (0.78) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL4211352 0.80 ALDH1A1 (0.78) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL4209148 0.78 ALDH1A1 (0.69) MAPTALDH1A1HPGDKMT2AMEN1
SCHEMBL4213284 0.76 MAPT (0.68) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL22018553 0.75 USP2 (0.79) MAPTALDH1A1HPGDTP53KMT2A
SCHEMBL4199726 0.75 HSD17B10 (0.67) MAPTALDH1A1HPGDTP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225979-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT ODDITY LABS, LLC 2024-07-11 — — US disclosed
US-20240225979-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT ODDITY LABS, LLC 2024-07-11 — — US disclosed
WO-2024147995-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT ODDITY LABS, LLC (US) 2024-07-11 — — WO disclosed
US-20230122670-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT ODDITY LABS, LLC 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122670-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT SUCLG1, SHH, NGF MAPT 550/4885ALDH1A1 983/4885HPGD 759/4885
US-20240225979-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT SUCLG1, NGF, CUTA MAPT 551/4885ALDH1A1 900/4885HPGD 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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