Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139050 | 0.85 | SCN9A (0.30) | GRM5 | |
| SCHEMBL20698935 | 0.83 | THRA (0.40) | LNPEP | |
| SCHEMBL23319862 | 0.82 | SCN9A (0.38) | GRM5LNPEP | |
| SCHEMBL25066945 | 0.80 | GRM5 (0.34) | GRM5 | |
| SCHEMBL23319823 | 0.78 | CACNA1B (0.35) | LNPEP | |
| SCHEMBL10608901 | 0.74 | MEN1 (0.38) | GRM5LNPEP | |
| SCHEMBL10612742 | 0.69 | GRM5 (0.35) | GRM5LNPEP | |
| SCHEMBL25138856 | 0.68 | HDAC1 (0.35) | LNPEP | |
| SCHEMBL14494186 | 0.68 | ALDH1A1 (0.39) | GRM5LNPEP | |
| SCHEMBL4965535 | 0.67 | GRM5 (0.43) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658538-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-04-19 | — | — | EP | disclosed |