Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25066945 | 0.78 | GRM5 (0.34) | MEN1KMT2AGRM5 | |
| SCHEMBL10612742 | 0.77 | GRM5 (0.35) | MEN1KMT2AGSRLNPEPGRM5 | |
| SCHEMBL28657835 | 0.77 | GSR (0.44) | MEN1KMT2AGSRMAPTCA1 | |
| SCHEMBL11658801 | 0.76 | CYP2D6 (0.51) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL20698935 | 0.75 | THRA (0.40) | MEN1KMT2ALNPEP | |
| SCHEMBL25139028 | 0.74 | GRM5 (0.31) | LNPEPGRM5 | |
| SCHEMBL23319862 | 0.74 | SCN9A (0.38) | MEN1KMT2ALNPEPGRM5 | |
| SCHEMBL14494186 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AGSRMAPTLNPEP | |
| SCHEMBL25139050 | 0.72 | SCN9A (0.30) | GRM5 | |
| SCHEMBL11065417 | 0.72 | ALOX5 (0.41) | MEN1KMT2AMAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754077-A | HINDERED PHENOLS, METHANOL, FORMALDEHYDE, PHENOL COMPOUND, MANNICH BASE CATALYST | ETHYL CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0116712-B1 | SYNTHESIS OF HINDERED PHENOLS | ETHYL CORPORATION (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0116712-A1 | Synthesis of hindered phenols | ETHYL CORPORATION (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984002336-A1 | ANTIOXIDANT SYNTHESIS | ETHYL CORP (US) | 1984-06-21 | — | — | WO | disclosed |