Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 15/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25459969 | 0.84 | CTSK (0.48) | CTSSCTSKBACE1CA2 | |
| SCHEMBL23106074 | 0.83 | CTSK (0.50) | CTSSCTSKBACE1CA2 | |
| SCHEMBL14012280 | 0.82 | CTSS (0.52) | CTSSCTSKBACE1CA2 | |
| SCHEMBL12283739 | 0.82 | CTSS (0.52) | CTSSCTSKBACE1CA2 | |
| SCHEMBL17902991 | 0.82 | CTSS (0.52) | CTSSCTSKBACE1CA2 | |
| SCHEMBL17581833 | 0.82 | CTSS (0.52) | CTSSCTSKBACE1CA2 | |
| SCHEMBL13436631 | 0.82 | CTSS (0.52) | CTSSCTSKBACE1CA2 | |
| SCHEMBL17209941 | 0.81 | CTSK (0.48) | CTSSCTSKBACE1CA2 | |
| SCHEMBL28342732 | 0.81 | CTSK (0.48) | CTSSCTSKBACE1CA2 | |
| SCHEMBL25140428 | 0.80 | CTSS (0.40) | CTSSCTSKBACE1CA2BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061482-A1 | EPHA2 BICYCLIC PEPTIDE LIGAND AND CONJUGATE THEREOF | 海思科医药集团股份有限公司 | 2023-04-20 | — | — | WO | disclosed |