Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209941 | 1.00 | CTSK (0.48) | CTSKCTSSPSENENCA2MEN1 | |
| SCHEMBL23106074 | 0.91 | CTSK (0.50) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL13436631 | 0.90 | CTSS (0.52) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL14012280 | 0.90 | CTSS (0.52) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL12283739 | 0.90 | CTSS (0.52) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL17902991 | 0.90 | CTSS (0.52) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL17581833 | 0.90 | CTSS (0.52) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL25459969 | 0.89 | CTSK (0.48) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL23998665 | 0.86 | CTSS (0.51) | CTSKCTSSCA2MEN1GAA | |
| SCHEMBL28974946 | 0.86 | CTSS (0.52) | CTSKCTSSPSENENCA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108650882-B | Compositions for treating cancers expressing IGF-1R | 皮埃尔法布雷医药公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-106470708-B | Antibody-drug-conjugates and their use for the treatment of cancer | 皮埃尔法布雷医药公司 | 2019-12-31 | — | — | CN | disclosed |