Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514942 | 0.91 | GRM1 (0.36) | GRM1DHFRPDE4DPDE4APDE4B | |
| SCHEMBL2511946 | 0.90 | GRM1 (0.35) | GRM1DHFRPDE4DPDE4APDE4B | |
| SCHEMBL2511926 | 0.90 | GRM1 (0.35) | GRM1DHFRPDE4DPDE4APDE4B | |
| SCHEMBL2510936 | 0.83 | SMYD3 (0.36) | GRM1DHFR | |
| SCHEMBL2512608 | 0.82 | HPGD (0.38) | GRM1 | |
| SCHEMBL2514854 | 0.81 | GRM1 (0.36) | GRM1DHFRTP53HSD17B10 | |
| SCHEMBL2511075 | 0.80 | MEN1 (0.39) | DHFRPDE4ATP53HSD17B10 | |
| SCHEMBL618494 | 0.80 | KAT2B (0.43) | DCPSMAPK1DHFRPIK3CAPDE4D | |
| SCHEMBL2514616 | 0.78 | MAP4K4 (0.36) | GRM1TP53HSD17B10 | |
| SCHEMBL2512977 | 0.78 | XDH (0.35) | GRM1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | DCPS 1214/4885GRM1 979/4885MAPK1 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.