Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | USP8 | P40818 | 2/20 | 0.66 |
| ▸ | ACLY | P53396 | 8/20 | 0.64 |
| ▸ | KDM1A | O60341 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988524 | 0.86 | ACLY (0.75) | USP2USP8ACLYKDM1AKMT2A | |
| SCHEMBL30806174 | 0.82 | ACLY (0.52) | USP2USP8ACLYSORT1PIK3CG | |
| SCHEMBL25140692 | 0.82 | ACLY (0.52) | USP2USP8ACLYSORT1PIK3CG | |
| SCHEMBL30547616 | 0.82 | USP2 (0.59) | USP2USP8ACLYKDM1AKMT2A | |
| SCHEMBL23877565 | 0.82 | USP2 (0.59) | USP2USP8ACLYKDM1AKMT2A | |
| SCHEMBL23879630 | 0.80 | USP2 (0.57) | USP2USP8ACLYKDM1AKMT2A | |
| SCHEMBL25140578 | 0.80 | USP2 (1.00) | USP2USP8ACLYKMT2A | |
| SCHEMBL19848269 | 0.79 | KMT2A (0.60) | USP2USP8KMT2ATSHRCKS1B | |
| SCHEMBL21931083 | 0.78 | ACLY (1.00) | ACLYKDM1AKMT2AMEN1GAA | |
| SCHEMBL23141212 | 0.78 | KDM1A (0.72) | USP2USP8ACLYKDM1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912595-B | Compound containing thiazole or thiadiazole structure and application thereof | 中国药科大学 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023061051-A1 | SULFAMIDE USP8 INHIBITOR AND USE THEREOF | 中国药科大学 | 2023-04-20 | — | — | WO | disclosed |
| CN-113912595-A | Compound containing thiazole or thiadiazole structure and application thereof | 中国药科大学 | 2022-01-11 | — | — | CN | disclosed |