SCHEMBL23879630

SCHEMBL23879630

C=C(CCNC(=O)c1ccc(C(F)(F)F)cc1NS(=O)(=O)c1cccnc1)C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 4/20 0.57
▸ USP8 P40818 4/20 0.57
▸ KMT2A Q03164 2/20 0.48
▸ ACLY P53396 2/20 0.45
▸ SORT1 Q99523 1/20 0.44
▸ NAMPT P43490 4/20 0.44
▸ TSHR P16473 1/20 0.44
▸ KDM1A O60341 1/20 0.43
▸ USP36 Q9P275 1/20 0.42
▸ CKS1B P61024 1/20 0.41
▸ SKP2 Q13309 1/20 0.41
▸ MCL1 Q07820 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23879530 0.89 ACLY (0.52) USP2USP8KMT2AACLYKDM1A
SCHEMBL24268165 0.84 KDM1A (0.51) USP2USP8KMT2AACLYKDM1A
SCHEMBL23879571 0.83 KDM1A (0.50) USP2USP8ACLYKDM1AUSP36
SCHEMBL23879629 0.83 KDM1A (0.50) USP2USP8ACLYKDM1AUSP36
SCHEMBL24268128 0.82 KDM1A (0.49) USP2USP8ACLYKDM1AUSP36
SCHEMBL23879544 0.82 KDM1A (0.49) USP2USP8ACLYKDM1AUSP36
SCHEMBL23879572 0.81 MCL1 (0.44) KMT2AACLYKDM1AMCL1KDM4E
SCHEMBL23879609 0.81 KDM1A (0.48) USP2USP8KMT2AACLYKDM1A
SCHEMBL24268146 0.81 KDM1A (0.48) USP2USP8ACLYKDM1AUSP36
SCHEMBL25140639 0.80 USP2 (0.66) USP2USP8KMT2AACLYSORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B USP2 3178/4885USP8 3142/4885KMT2A 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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