SCHEMBL25140770

SCHEMBL25140770

CC(C)(C)C1O[C@H](CO)[C@H](O)[C@H]1OC1O[C@H](CO)[C@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ MAPT P10636 1/20 0.49
▸ LGALS8 O00214 1/20 0.45
▸ LGALS3 P17931 1/20 0.45
▸ LGALS4 P56470 1/20 0.45
▸ GJA1 P17302 1/20 0.44
▸ GJB2 P29033 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ LMNA P02545 1/20 0.43
▸ POLB P06746 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ IGF2R P11717 1/20 0.40
▸ CD209 Q9NNX6 1/20 0.40
▸ SYNJ2 O15056 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16263450 0.95 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25140766 0.95 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL19781814 0.95 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25140877 0.95 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25705585 0.94 L3MBTL1 (0.46) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25692868 0.94 L3MBTL1 (0.51) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL19782039 0.94 L3MBTL1 (0.51) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25140762 0.92 LGALS3 (0.51) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25692854 0.92 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8
SCHEMBL25692944 0.92 L3MBTL1 (0.53) L3MBTL1MEN1KMT2AMAPTLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 — — US disclosed
US-20230124589-A1 Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis DOUBLERAINBOW BIOSCIENCES INC. 2023-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230124589-A1 Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis UGGT1, UGDH, GALE L3MBTL1 1359/4885MEN1 4138/4885KMT2A 3837/4885
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug GALE, UGGT1, DERA L3MBTL1 1063/4885MEN1 1259/4885KMT2A 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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