Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25144727 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL25144724 | 0.87 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL25144719 | 0.82 | MAPT (0.46) | ALDH1A1KMT2AMEN1RAB9APOLB | |
| SCHEMBL19762359 | 0.81 | KDM4E (0.46) | ALDH1A1KMT2AMEN1POLBHSD17B10 | |
| SCHEMBL13256453 | 0.79 | TDP1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16601847 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1RAB9APOLB | |
| SCHEMBL15923240 | 0.79 | TDP1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12661123 | 0.79 | TDP1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13256445 | 0.79 | TDP1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29384887 | 0.79 | TDP1 (0.58) | KMT2AMEN1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | RNGTT, SSU72, NSUN2 | ALDH1A1 3898/4885KMT2A 1141/4885MEN1 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.