Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.65 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 9/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206476 | 0.81 | CCR2 (0.64) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL1573798 | 0.80 | PLA2G10 (0.78) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL25145010 | 0.78 | CCR2 (0.67) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL30044340 | 0.77 | CCR2 (0.58) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL13738783 | 0.77 | CCR2 (0.58) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL13127957 | 0.77 | CCR2 (0.59) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL3647083 | 0.76 | PLA2G10 (0.71) | CCR2PLA2G10F10F2 | |
| SCHEMBL27837248 | 0.76 | CCR2 (0.46) | CCR2PLA2G10F10KMT2A | |
| SCHEMBL25145298 | 0.75 | CCR2 (0.61) | CCR2F10NOD2NOD1KMT2A | |
| SCHEMBL29933820 | 0.74 | HDAC6 (0.70) | CCR2PLA2G10F10HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |