Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.67 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 8/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573798 | 0.85 | PLA2G10 (0.78) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL28206476 | 0.80 | CCR2 (0.64) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL30622530 | 0.79 | HDAC3 (0.53) | CCR2PLA2G10F10HDAC1 | |
| SCHEMBL20609049 | 0.79 | HDAC3 (0.53) | CCR2PLA2G10F10HDAC1 | |
| SCHEMBL29933820 | 0.79 | HDAC6 (0.70) | CCR2PLA2G10F10HDAC1HDAC2 | |
| SCHEMBL25145299 | 0.78 | CCR2 (0.65) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL27636281 | 0.77 | CCR2 (0.54) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL27636282 | 0.77 | PLA2G10 (0.56) | CCR2PLA2G10F10NOD2NOD1 | |
| SCHEMBL30229413 | 0.76 | NOD2 (0.43) | CCR2F10NOD2NOD1KMT2A | |
| SCHEMBL20839563 | 0.76 | NOD2 (0.43) | CCR2F10NOD2NOD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |