Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30553348 | 0.79 | P2RX7 (0.30) | — | |
| Hydrochloric Acid SCHEMBL25326885 | 0.78 | — | — | |
| SCHEMBL15421898 | 0.75 | GNAI3 (0.49) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL22722874 | 0.75 | GNAI3 (0.41) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28439551 | 0.73 | GNAI3 (0.51) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 | |
| SCHEMBL21608592 | 0.73 | GNAI3 (0.48) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 | |
| SCHEMBL30298825 | 0.73 | GNAI3 (0.44) | GNAI3GNAO1GNAI1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25944777 | 0.72 | GNAI3 (0.39) | GNAI3GNAO1GNAI1EPHX2GABRA1 | |
| SCHEMBL25145686 | 0.71 | DPP7 (0.39) | GNAI3GNAO1GNAI1 | |
| SCHEMBL5783422 | 0.71 | GNAI3 (0.42) | GNAI3GNAO1GNAI1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |