Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409945 | 0.91 | MGLL (0.48) | MGLLSCN9AAKR1C3 | |
| SCHEMBL25145896 | 0.89 | MEN1 (0.43) | MGLLSCN9APKMMEN1KMT2A | |
| SCHEMBL25146099 | 0.88 | SCN9A (0.44) | MGLLSCN9APKMALDH1A1AKR1C3 | |
| SCHEMBL25146248 | 0.85 | SCN9A (0.47) | MGLLSCN9APKMALDH1A1AKR1C3 | |
| SCHEMBL25145990 | 0.83 | CHRM1 (0.44) | MGLLPKMALDH1A1AKR1C3MEN1 | |
| SCHEMBL30409598 | 0.80 | MGLL (0.41) | MGLLAKR1C3MEN1KMT2APOLB | |
| SCHEMBL25146054 | 0.79 | MGLL (0.48) | MGLLAKR1C3PKLR | |
| SCHEMBL30409338 | 0.79 | AKR1C3 (0.40) | MGLLSCN9AAKR1C3MEN1KMT2A | |
| SCHEMBL30408465 | 0.78 | SCN9A (0.41) | MGLLSCN9AAKR1C3MEN1KMT2A | |
| SCHEMBL25145596 | 0.76 | L3MBTL1 (0.42) | MGLLALDH1A1GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |