Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146247 | 0.94 | FAAH (0.44) | ENPP2ATXN2MGLLFAAHGPR183 | |
| SCHEMBL25146037 | 0.93 | MGLL (0.45) | MGLLFAAHCYP2D6PDCD1LG2CD274 | |
| SCHEMBL30409906 | 0.93 | MGLL (0.41) | ENPP2ATXN2MGLLFAAHGPR183 | |
| SCHEMBL25146318 | 0.85 | MGLL (0.46) | ENPP2ATXN2MGLLFAAHGPR183 | |
| SCHEMBL30409855 | 0.85 | MGLL (0.46) | ENPP2ATXN2MGLLFAAHGPR183 | |
| SCHEMBL30409323 | 0.81 | MGLL (0.43) | ENPP2ATXN2MGLLTSHRALDH1A1 | |
| SCHEMBL25146106 | 0.81 | PPARG (0.40) | MGLLGPR183CYP3A4CYP2D6TSHR | |
| SCHEMBL25146124 | 0.81 | MGLL (0.43) | ENPP2ATXN2MGLLTSHRALDH1A1 | |
| SCHEMBL25253780 | 0.81 | FAAH (0.47) | ENPP2ATXN2MGLLFAAHGPR183 | |
| SCHEMBL30409293 | 0.80 | FAAH (0.42) | ENPP2ATXN2MGLLFAAHGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416154-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-08-21 | — | — | EP | claimed |
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | claimed |
| EP-4416154-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-08-21 | — | — | EP | disclosed |
| CN-118103374-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |