Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409323 | 1.00 | MGLL (0.43) | MGLLCACNA1BPKMPLA2G1BATG4B | |
| SCHEMBL25145968 | 0.88 | CACNA1B (0.40) | MGLLCACNA1BPKMPLA2G1BATG4B | |
| SCHEMBL25146103 | 0.86 | CACNA1B (0.41) | MGLLCACNA1BPKMPLA2G1BATG4B | |
| SCHEMBL30409788 | 0.85 | MGLL (0.44) | MGLLCACNA1BPKM | |
| SCHEMBL25253376 | 0.82 | CACNA1B (0.48) | CACNA1BPKMPLA2G1BATG4BALDH1A1 | |
| SCHEMBL25146284 | 0.81 | ENPP2 (0.42) | MGLLALDH1A1TSHRENPP2ATXN2 | |
| SCHEMBL25146247 | 0.79 | FAAH (0.44) | MGLLALDH1A1CYP2C9TSHRENPP2 | |
| SCHEMBL31308002 | 0.78 | EPHX2 (0.42) | MGLLCACNA1BALDH1A1TRPV4CYP2C9 | |
| SCHEMBL25327528 | 0.78 | CACNA1B (0.40) | MGLLCACNA1BPKMPLA2G1BATG4B | |
| SCHEMBL25296539 | 0.78 | F13A1 (0.50) | CACNA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |