SCHEMBL2514718

SCHEMBL2514718

OCc1ccc(CO)c(O)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
CASP6 P55212 1/20 0.39
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
SHBG P04278 1/20 0.37
HSD17B10 Q99714 2/20 0.36
PDXK O00764 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
KLF10 Q13118 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2510833 0.88 KDM4E (0.42) KDM4ELMNANPC1GAAHTT
SCHEMBL10912412 0.82 KDM4E (0.45) KDM4ECASP6LMNANPC1GAA
SCHEMBL29493008 0.82 KDM4E (0.45) KDM4ECASP6LMNANPC1GAA
SCHEMBL28762559 0.82 PRKCI (0.50) HTTALOX15GABRA1GABRB2TP53
SCHEMBL196227 0.80 GABRA1 (0.57) KDM4ELMNAAPOBEC3GHSD17B10ALDH1A1
SCHEMBL5468115 0.78 KDM4E (0.39) KDM4ELMNANPC1GAAHTT
SCHEMBL12201590 0.76 KDM4E (0.48) KDM4ECASP6LMNASHBGHSD17B10
SCHEMBL3144290 0.76 MEP1B (0.39) KDM4ECASP6LMNANPC1GAA
SCHEMBL29367192 0.76 SHBG (0.42) KDM4ELMNASHBGHSD17B10PDXK
SCHEMBL10771987 0.76 MAPK1 (0.42) LMNANPC1HTTSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009517514-A 2009-04-30 JP claimed
CN-101316893-A Formaldehyde-free phenolic resin binder SAINT GOBAIN ISOVER (FR) 2008-12-03 CN claimed
EP-1957580-A1 FORMALDEHYDE-FREE PHENOLIC RESIN BINDER. SAINT-GOBAIN ISOVER (FR) 2008-08-20 EP claimed
WO-2007060237-A1 FORMALDEHYDE-FREE PHENOLIC RESIN BINDER. SAINT-GOBAIN ISOVER (FR) 2007-05-31 WO claimed
CN-101316893-B Formaldehyde-free phenolic resin binder SAINT GOBAIN ISOVER 2013-03-13 CN disclosed
US-8034415-B2 Formaldehyde-free phenolic resin binder SAINT-GOBAIN ISOVER (FR) 2011-10-11 US disclosed
US-20090304919-A1 FORMALDEHYDE-FREE PHENOLIC RESIN BINDER SAINT-GOBAIN ISOVER (FR) 2009-12-10 US disclosed
CN-101316893-A Formaldehyde-free phenolic resin binder SAINT GOBAIN ISOVER (FR) 2008-12-03 CN disclosed
EP-1957580-A1 FORMALDEHYDE-FREE PHENOLIC RESIN BINDER. SAINT-GOBAIN ISOVER (FR) 2008-08-20 EP disclosed
WO-2007060237-A1 FORMALDEHYDE-FREE PHENOLIC RESIN BINDER. SAINT-GOBAIN ISOVER (FR) 2007-05-31 WO disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed