Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ASPH | Q12797 | 2/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15168790 | 0.88 | KDM4E (0.54) | KDM4ESMN1; SMN2ASPHKDM8AURKA | |
| SCHEMBL2018336 | 0.88 | KDM4E (0.76) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL2514856 | 0.83 | KDM4E (0.55) | KDM4ESMN1; SMN2ASPHKDM8AURKA | |
| SCHEMBL16105916 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2 | |
| SCHEMBL2017818 | 0.81 | KDM4E (0.82) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL7375582 | 0.79 | KDM4E (0.53) | KDM4ESMN1; SMN2ASPHKDM8AURKA | |
| SCHEMBL23575222 | 0.78 | MAPT (0.53) | KDM4ESMN1; SMN2ASPHKDM8RIOX2 | |
| Phosphoric Acid SCHEMBL11249952 | 0.78 | KDM4E (0.76) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9320011 | 0.77 | KDM4E (0.64) | KDM4ESMN1; SMN2 | |
| SCHEMBL15170185 | 0.76 | GAA (0.63) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | claimed |
| CN-102933081-A | Sweet flavor modifier | SENOMYX INC | 2013-02-13 | — | — | CN | claimed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | claimed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | claimed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | claimed |
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| CN-102933081-B | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-04-13 | — | — | CN | disclosed |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2015-09-24 | — | — | US | disclosed |
| US-9049878-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| CN-102933081-A | Sweet flavor modifier | SENOMYX INC | 2013-02-13 | — | — | CN | disclosed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885SMN1; SMN2 2246/4885ASPH 1941/4885 |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885SMN1; SMN2 2246/4885ASPH 1941/4885 |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885SMN1; SMN2 2246/4885ASPH 1941/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | KDM4E 1475/4885SMN1; SMN2 2246/4885ASPH 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.