SCHEMBL25147667

SCHEMBL25147667

C=c1c(Nc2ccccc2)ccc/c1=C/C=C\C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.42
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
GAA P10253 5/20 0.42
TDP1 Q9NUW8 5/20 0.42
KDM4E B2RXH2 3/20 0.42
GLA P06280 1/20 0.42
RECQL P46063 1/20 0.42
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 4/20 0.39
ALOX15 P16050 3/20 0.39
HPGD P15428 3/20 0.39
TSHR P16473 2/20 0.39
ATM Q13315 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CDC25B P30305 1/20 0.39
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26146865 1.00 MAPT (0.42) MAPTMEN1KMT2AGAATDP1
SCHEMBL25141761 0.83 MAPT (0.47) MAPTMEN1KMT2AGAATDP1
SCHEMBL24373992 0.82 MAPT (0.46) MAPTMEN1KMT2AGAATDP1
SCHEMBL22166177 0.68 MAPT (0.48) MAPTMEN1KMT2AGAATDP1
SCHEMBL18175860 0.68
SCHEMBL23544001 0.66 ALDH1A1 (0.37) MAPTMEN1KMT2AGAATDP1
SCHEMBL23128892 0.66 ALDH1A1 (0.37) MAPTMEN1KMT2AGAATDP1
SCHEMBL19055860 0.65 MAPT (0.44) MAPTMEN1KMT2AGAATDP1
SCHEMBL14419935 0.65
SCHEMBL444976 0.64 MAPT (0.70) MAPTMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230148324-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-05-11 US disclosed
US-20230124167-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed