SCHEMBL22166177

SCHEMBL22166177

C/C=c1/cccc(Nc2ccccc2)/c1=C/C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
GAA P10253 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
KDM4E B2RXH2 3/20 0.48
GLA P06280 1/20 0.48
RECQL P46063 1/20 0.48
ALDH1A1 P00352 6/20 0.44
HSD17B10 Q99714 4/20 0.44
ALOX15 P16050 3/20 0.44
HPGD P15428 3/20 0.44
TSHR P16473 2/20 0.44
ATM Q13315 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
CDC25B P30305 1/20 0.44
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19055860 0.88 MAPT (0.44) MAPTMEN1KMT2AGAATDP1
SCHEMBL25141761 0.80 MAPT (0.47) MAPTMEN1KMT2AGAATDP1
SCHEMBL22383857 0.76 MAPT (0.35) MAPTTDP1KDM4ERECQLALDH1A1
SCHEMBL22642309 0.72 MEN1 (0.37) MEN1KMT2ARECQLTSHRCYP3A4
SCHEMBL444976 0.70 MAPT (0.70) MAPTMEN1KMT2AGAATDP1
SCHEMBL25147667 0.68 MAPT (0.42) MAPTMEN1KMT2AGAATDP1
SCHEMBL24373992 0.68 MAPT (0.46) MAPTMEN1KMT2AGAATDP1
SCHEMBL28194057 0.67 PDCD1 (0.41) MEN1KMT2AALDH1A1HSD17B10HPGD
SCHEMBL28969955 0.66 MAPT (0.65) MAPTMEN1KMT2AGAATDP1
SCHEMBL6404861 0.66 MEN1 (1.00) MAPTMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10700284-B2 Photoactive composition LG CHEM, LTD. (KR) 2020-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10700284-B2 Photoactive composition L1CAM, EPCAM, GJB2 MAPT 1012/4885MEN1 2970/4885KMT2A 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.