SCHEMBL24373992

SCHEMBL24373992

C=C/C=c1/cccc(Nc2ccccc2)c1=C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.46
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
TDP1 Q9NUW8 7/20 0.46
KDM4E B2RXH2 5/20 0.46
GAA P10253 5/20 0.46
GLA P06280 2/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 8/20 0.42
ALOX15 P16050 4/20 0.42
HSD17B10 Q99714 3/20 0.42
TSHR P16473 3/20 0.42
HPGD P15428 3/20 0.42
CYP3A4 P08684 3/20 0.42
ATM Q13315 2/20 0.42
TP53 P04637 1/20 0.42
CDC25B P30305 1/20 0.42
LMNA P02545 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25147667 0.82 MAPT (0.42) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL26146865 0.82 MAPT (0.42) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL25141761 0.81 MAPT (0.47) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL22166177 0.68 MAPT (0.48) MAPTMEN1KMT2ATDP1KDM4E
Diphenylamine SCHEMBL8598836 0.68 HSD17B10 (0.71) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL444976 0.67 MAPT (0.70) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL18499741 0.67 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL25141469 0.66 ALDH1A1 (0.35) MAPTTDP1KDM4ERECQLALDH1A1
SCHEMBL291979 0.66 MAPT (0.50) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL19055860 0.64 MAPT (0.44) MAPTMEN1KMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230200207-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230124167-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
US-20230123928-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
US-20220127288-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed
EP-3988556-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG Display Co., Ltd. (KR) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127288-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND OCIAD1, OCIAD2, OXA1L MAPT 427/4885MEN1 1309/4885KMT2A 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.