Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25497019 | 0.92 | FAAH (0.60) | FAAHPSMB5EPHX2CTSBGRIA1 | |
| SCHEMBL25496878 | 0.88 | FAAH (0.53) | FAAHPSMB5EPHX2GRIA1CHRNB2 | |
| SCHEMBL23718554 | 0.88 | FAAH (0.58) | FAAHPSMB5EPHX2 | |
| SCHEMBL23718677 | 0.87 | FAAH (0.52) | FAAHPSMB5EPHX2OPRM1OPRD1 | |
| SCHEMBL26154325 | 0.87 | FAAH (0.52) | FAAHPSMB5EPHX2 | |
| SCHEMBL26154311 | 0.87 | FAAH (0.52) | FAAHPSMB5EPHX2 | |
| SCHEMBL24982489 | 0.86 | FAAH (0.69) | FAAHPSMB5EPHX2 | |
| SCHEMBL25494040 | 0.85 | FAAH (0.48) | FAAHPSMB5EPHX2OPRM1OPRD1 | |
| SCHEMBL19650462 | 0.85 | FAAH (0.59) | FAAHPSMB5EPHX2 | |
| SCHEMBL24879511 | 0.85 | FAAH (0.65) | FAAHPSMB5CTSBGRIA1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061405-A1 | HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE | 成都科岭源医药技术有限公司 | 2023-04-20 | — | — | WO | disclosed |