SCHEMBL25149587

SCHEMBL25149587

COC(=O)c1cc(C)c2nccn2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
SYK P43405 6/20 0.41
JMJD6 Q6NYC1 1/20 0.40
ALDH1A1 P00352 3/20 0.39
GAA P10253 2/20 0.39
PPARG P37231 1/20 0.39
MAPK10 P53779 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
STING1 Q86WV6 1/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 3/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16829238 0.85 KDM4E (0.44) SYKJMJD6ALDH1A1GAAPPARG
SCHEMBL20843630 0.84 ALDH1A1 (0.49) L3MBTL1JMJD6ALDH1A1GAAPPARG
SCHEMBL5327078 0.84 MAOB (0.40) L3MBTL1SYKJMJD6ALDH1A1GAA
SCHEMBL6489509 0.83 L3MBTL1 (0.56) L3MBTL1SYKJMJD6RXFP1KDM4C
SCHEMBL27399575 0.82 TRIM33 (0.39) L3MBTL1SYKJMJD6ALDH1A1GAA
SCHEMBL23029794 0.82 L3MBTL1 (0.51) L3MBTL1SYK
SCHEMBL23029791 0.81 L3MBTL1 (0.54) L3MBTL1SYKLMNA
SCHEMBL23029808 0.79 L3MBTL1 (0.51) L3MBTL1SYKALDH1A1GAAKMT2A
SCHEMBL16828787 0.77 SYK (0.35) L3MBTL1SYKJMJD6ALDH1A1GAA
SCHEMBL30871543 0.77 SYK (0.35) L3MBTL1SYKJMJD6ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695245-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4694686-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4695244-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
EP-4634178-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-22 EP disclosed
US-20240425500-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-12-26 US disclosed
WO-2024213650-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed
WO-2024213720-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed
WO-2024213651-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
WO-2024126404-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO disclosed
CN-118043321-A Imidazo [1,2-a ] pyridine derivatives 先正达农作物保护股份公司 2024-05-14 CN disclosed
WO-2023061838-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425500-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES IDO1, CYP1A1, CYP4Z1 L3MBTL1 2306/4885SYK 664/4885JMJD6 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.