SCHEMBL2515265

SCHEMBL2515265

C1=CCC2(C=C1)c1ccccc1-c1ccccc12

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.33
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 2/20 0.31
S100A4 P26447 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31549870 0.77 SLC6A3 (0.39) TDP1KMT2AKDM4EMEN1MAPT
SCHEMBL2283117 0.74 HDAC4 (0.34) KMT2AMEN1OPRK1
Ethylene SCHEMBL27402897 0.71 HDAC4 (0.32) OPRK1
Biphenyl SCHEMBL28885424 0.69 ALDH1A1 (0.36)
SCHEMBL6421730 0.67 SLC6A2 (0.40) PDK2THRBTDP1
SCHEMBL4413275 0.67 ALDH1A1 (0.34) THRBTDP1
SCHEMBL17727866 0.67 ALDH1A1 (0.34) THRBTDP1
SCHEMBL30663214 0.66 KDM1A (0.36) TDP1LMNAMAPTOPRK1SMN1; SMN2
SCHEMBL9068306 0.66
SCHEMBL11881975 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110240965-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-10-06 US claimed
US-7776457-B2 A OLED layer composed of phosphorescent dopant disposed between a first electrode and a second electrode; and a blue light emitting layer contacting the light emitting layer, wherein the light emitting layer has a hole transport material and an electron transport material as a host SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US claimed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US claimed
US-20110240965-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-10-06 US disclosed
US-7776457-B2 A OLED layer composed of phosphorescent dopant disposed between a first electrode and a second electrode; and a blue light emitting layer contacting the light emitting layer, wherein the light emitting layer has a hole transport material and an electron transport material as a host SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-08-17 US disclosed
US-7651790-B2 bipolar phosphorescent host containing 4,4'-biscarbazolylbiphenyl hole transport unit attached to electron transport unit selected from fluorene or spirofluorene and an aluminum hydroquinoline unit; phospherescent dopant e.g. tris(3-biphenylpyridine)Iridium; high efficiency and a long lifetime SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
US-20060263631-A1 bipolar phosphorescent host containing 4,4'-biscarbazolylbiphenyl hole transport unit attached to electron transport unit selected from fluorene or spirofluorene and an aluminum hydroquinoline unit; phospherescent dopant e.g. tris(3-biphenylpyridine)Iridium; high efficiency and a long lifetime SAMSUNG SDI CO., LTD. 2006-11-23 US disclosed
US-20060105201-A1 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2006-05-18 US disclosed