⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406785 | 1.00 | — | — | |
| Bromide SCHEMBL5756007 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30751932 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1768191 | 0.97 | — | — | |
| SCHEMBL10379326 | 0.91 | NOS3 (0.83) | — | |
| SCHEMBL8591456 | 0.91 | NOS3 (0.83) | — | |
| SCHEMBL2853785 | 0.89 | NOS3 (0.79) | — | |
| Pyridine SCHEMBL5164941 | 0.87 | NOS2 (0.76) | — | |
| Dalfampridine SCHEMBL9491048 | 0.87 | NOS3 (0.76) | — | |
| SCHEMBL29008548 | 0.82 | NOS1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6188 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503470-B2 | Preparation of a P2X3 antagonist | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2025-12-23 | — | — | US | claimed |
| CN-119899194-B | Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof | 浙江省人民医院 | 2025-06-24 | — | — | CN | claimed |
| CN-120081843-A | Fluorescent probe for quantitatively detecting NO in exhaled breath, and preparation method and application thereof | 阜阳师范大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119899194-A | Bicyclic heteroaryl BRAF negative allosteric modulator, and preparation method and application thereof | 浙江省人民医院 | 2025-04-29 | — | — | CN | claimed |
| CN-119798591-A | Shape memory polymer with high stretching capability and preparation method thereof | 哈尔滨工业大学 | 2025-04-11 | — | — | CN | claimed |
| CN-119790042-A | Preparation of P2X3 antagonists | 葛兰素史密斯克莱知识产权(第3号)有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-118726960-B | Colloid palladium activator and preparation method thereof and electroless copper plating process | 惠州市荣安达化工有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-115458314-B | Organic material coated microcapsule composite carbonyl iron powder and preparation method thereof | 电子科技大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118988194-A | System and process for synthesizing 3- (methacryloyloxy) propyl trimethoxy silane | 江西宏柏新材料股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| US-20240351992-A1 | PREPARATION OF P2X3 ANTAGONIST | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2024-10-24 | — | — | US | claimed |
| EP-0196522-A1 | 2-Amino-4-trichloromethyl pyridine, process for its preparation and its use as a nitrification inhibitor | BASF Aktiengesellschaft (DE) | 1986-10-08 | — | — | EP | claimed |
| US-4610982-A | Anti-inflammatory benzo- and thieno-1,2-thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor | PFIZER INC. (US) | 1986-09-09 | — | — | US | claimed |
| US-4601797-A | Electrochemical carboxylation of p-isobutylacetophenone and other aryl ketones | MONSANTO COMPANY (US) | 1986-07-22 | — | — | US | claimed |
| US-4594413-A | Preparation of N,N'-methylene-2,2'-azopyridocyanines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1986-06-10 | — | — | US | claimed |
| US-4188491-A | PREPARING 2-(4-BIPHENYLYL)PROPIONIC ACIDS BY REACTING BIPHENYLYLMAGNESIUM BROMIDES WITH SODIUM PYRUVATE, ACIDIFYING | THE BOOTS COMPANY LIMITED (GB) | 1980-02-12 | — | — | US | claimed |
| US-4107439-A | Process for preparing arylalkanoic acid derivatives | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | claimed |
| US-4096338-A | ANTIPHLOGISTIC | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1978-06-20 | — | — | US | claimed |
| US-4042617-A | FROM A GLYCIDIC ACID ESTER | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-08-16 | — | — | US | claimed |
| US-4007217-A | FROM A GLYCIDATE | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-02-08 | — | — | US | claimed |
| US-3966726-A | Process for the production of cyclic carboxylic acid imides | AKZO N.V. (NL) | 1976-06-29 | — | — | US | claimed |