Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78479 | 0.84 | HTR7 (0.53) | HTR7CDK4CCND1HTR2CHTR2A | |
| SCHEMBL20614497 | 0.80 | HTR1D (0.62) | HTR7HTR2CHTR2AHTR1D | |
| SCHEMBL26674331 | 0.79 | HTR7 (0.53) | HTR7HTR2CHTR2A | |
| SCHEMBL4651648 | 0.78 | KDM4E (0.53) | CDK4CCND1HTR2CHTR2AMTNR1A | |
| SCHEMBL8430623 | 0.78 | KMO (0.59) | HTR7CDK4CCND1HTR2CHTR2A | |
| SCHEMBL8434667 | 0.78 | HTR2C (0.56) | HTR7CDK4CCND1HTR2CHTR2A | |
| SCHEMBL19526836 | 0.78 | HTR7 (0.57) | HTR7RORARORCRORBCDK4 | |
| SCHEMBL27812843 | 0.78 | CDK4 (0.44) | CDK4CCND1HTR2CHTR2AHTR1D | |
| SCHEMBL26674340 | 0.76 | HTR7 (0.51) | HTR7HTR2CHTR2AL3MBTL1HTR1D | |
| SCHEMBL26053305 | 0.75 | HTR7 (0.45) | HTR7CDK4CCND1HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064345-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |