Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21315843 | 0.88 | RORC (0.47) | SLC6A4ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL21315844 | 0.88 | RORC (0.47) | SLC6A4ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2080509 | 0.84 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL8101234 | 0.84 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL1738860 | 0.84 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL6936570 | 0.82 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL1415727 | 0.82 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL27505917 | 0.82 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL3948948 | 0.81 | SIGMAR1 (0.54) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL23496876 | 0.81 | SIGMAR1 (0.54) | SLC6A2SLC6A4SLC6A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064768-A1 | G-PROTEIN-COUPLED RECEPTOR REGULATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-04-20 | — | — | WO | disclosed |