Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.57 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283405 | 1.00 | SIGMAR1 (0.57) | SIGMAR1RORCLMNAPOLBALDH1A1 | |
| SCHEMBL21315836 | 1.00 | SIGMAR1 (0.57) | SIGMAR1RORCLMNAPOLBALDH1A1 | |
| SCHEMBL10681973 | 0.89 | SIGMAR1 (0.55) | SIGMAR1LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL123695 | 0.85 | SIGMAR1 (0.61) | SIGMAR1LMNAPOLBALDH1A1GAA | |
| SCHEMBL8408488 | 0.84 | GBA1 (0.48) | SIGMAR1RORCPOLBALDH1A1KMT2A | |
| SCHEMBL25154296 | 0.84 | MC4R (0.49) | SIGMAR1ALDH1A1 | |
| SCHEMBL25154556 | 0.84 | SIGMAR1 (0.47) | SIGMAR1LMNAALDH1A1KMT2A | |
| SCHEMBL25154734 | 0.84 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1 | |
| SCHEMBL25154270 | 0.84 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1 | |
| SCHEMBL65364 | 0.83 | SIGMAR1 (0.78) | SIGMAR1LMNAPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064768-A1 | G-PROTEIN-COUPLED RECEPTOR REGULATORS AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-04-20 | — | — | WO | disclosed |