Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822485 | 0.90 | OPRD1 (0.53) | OPRD1FFAR1 | |
| SCHEMBL3689270 | 0.90 | OPRD1 (0.53) | OPRD1FFAR1 | |
| SCHEMBL15481709 | 0.89 | OPRD1 (0.58) | OPRD1SIGMAR1KMT2A | |
| SCHEMBL25154604 | 0.84 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2ARORCALDH1A1 | |
| SCHEMBL21315836 | 0.84 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2ARORCALDH1A1 | |
| SCHEMBL4283405 | 0.84 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2ARORCALDH1A1 | |
| SCHEMBL11990398 | 0.83 | SIGMAR1 (0.47) | GBA1OPRD1SIGMAR1POLBALDH1A1 | |
| SCHEMBL25154270 | 0.83 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1 | |
| SCHEMBL25154734 | 0.83 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1 | |
| SCHEMBL25154272 | 0.81 | CA1 (0.48) | SIGMAR1CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11046784-A | — | — | None | — | — | JP | disclosed |
| JP-H1146784-A | PRODUCTION OF OPTICALLY ACTIVE N-SUBSTITUTED AZETIDINE-2-CARBOXYLIC ACID COMPOUND | SUMITOMO CHEM CO LTD | 1999-02-23 | — | — | JP | disclosed |